EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

experimental allergic encephalomyelitis: translation

An autoimmune disease that can be induced in various experimental animals by the injection of homogenized brain or spinal cord in Freund\'s adjuvant. The antigen appears to be a basic protein present in myelin, and the response is characterized by focal areas of lymphocyte and macrophage infiltration into the brain, associated with demyelination and destruction of the blood-brain barrier. Sometimes used as a model for demyelinating diseases, although whether this is entirely justifiable is not clear.