CALCINEURIN
calcineurin: translation
Calmodulin-stimulated protein-phosphatase (EC 3.1.3.16), the major calmodulin-binding protein in brain. Enzymic activity is inhibited by binding of immunophilin-ligand complex (immunophilin alone does not bind) and therefore may play a part in the mechanism of action of cyclosporin A and FK506. Thought also to be involved in the control of sperm motility.