CYCLIC AMP
cyclic AMP: translation
(= cAMP)
3\'5\'-cyclic ester of AMP. The first second-messenger hormone signalling system to be characterized. Generated from ATP by the action of adenyl cyclase that is coupled to hormone receptors by G-proteins (GTP-binding proteins). cAMP activates a specific (cAMP dependent) protein kinase and is inactivated by phosphodiesterase action giving 5\'AMP. Also functions as an extracellular morphogen for some slime moulds.