ADDRESSINS

Cell surface molecules, particularly on endothelial cells believed to be involved in controlling the location of migrating cells, especially in lymphocyte homing. Probably act as cell adhesion molecules or their receptors. All have lectin, EGF, and complement-regulatory domains extracellularly in addition to the membrane spanning and cytoplasmic domains. Examples are ELAM-1, GMP-140 (PADGEM), gp90mel; also known as selectins.